Search on: RECEPTORS, PLATELET-DERIVED GROWTH FACTOR 
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Descriptor English:   Receptors, Platelet-Derived Growth Factor 
Descriptor Spanish:   Receptores del Factor de Crecimiento Derivado de Plaquetas 
Descriptor Portuguese:   Receptores do Fator de Crescimento Derivado de Plaquetas 
Synonyms English:   PDGF Receptor
PDGF Receptors
Platelet Derived Growth Factor Receptor
Platelet Derived Growth Factor Receptors
Platelet-Derived Growth Factor Receptor
Platelet-Derived Growth Factor Receptors
Receptor, PDGF
Receptors, PDGF
Receptors, Platelet Derived Growth Factor  
Tree Number:   D08.811.913.696.620.682.725.400.900
D12.776.543.750.630.625
D12.776.543.750.750.400.630
Definition English:   Specific receptors on cell membranes that react with PLATELET-DERIVED GROWTH FACTOR, its analogs, or antagonists. The alpha PDGF receptor (RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA) and the beta PDGF receptor (RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA) are the two principle types of PDGF receptors. Activation of the protein-tyrosine kinase activity of the receptors occurs by ligand-induced dimerization or heterodimerization of PDGF receptor types. 
See Related English:   Platelet-Derived Growth Factor
 
History Note English:   93; was PLATELET-DERIVED GROWTH FACTOR RECEPTOR (NM) 1982-92; PLATELET DERIVED GROWTH FACTOR RECEPTOR-KINASE was NM 1989-92 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   30547 
Unique Identifier:   D017479 

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